You are here
Home > Guest Post > What is CBD?

What is CBD? Take a closer look at the benefits of Cannabidiol (CBD) and how it is synthesized in the cannabis plant.


  • Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action.
    Zuardi AW1.
    Author information
    The aim of this review is to describe the historical development of research on cannabidiol.
    This review was carried out on reports drawn from Medline, Web of Science and SciELO.
    After the elucidation of the chemical structure of cannabidiol in 1963, the initial studies showed that cannabidiol was unable to mimic the effects of Cannabis. In the 1970's the number of publications on cannabidiol reached a first peak, having the research focused mainly on the interaction with delta9-THC and its antiepileptic and sedative effects. The following two decades showed lower degree of interest, and the potential therapeutic properties of cannabidiol investigated were mainly the anxiolytic, antipsychotic and on motor diseases effects. The last five years have shown a remarkable increase in publications on cannabidiol mainly stimulated by the discovery of its anti-inflammatory, anti-oxidative and neuroprotective effects. These studies have suggested a wide range of possible therapeutic effects of cannabidiol on several conditions, including Parkinson's disease, Alzheimer's disease, cerebral ischemia, diabetes, rheumatoid arthritis, other inflammatory diseases, nausea and cancer.
    In the last 45 years it has been possible to demonstrate that CBD has a wide range of pharmacological effects, many of which being of great therapeutic interest, but still waiting to be confirmed by clinical trials.

  • Antonio W. Zuardi, PhD, Vice Director, Department of Neurology and Medical Psychology, University of São Paulo

    "Cannabis as a medicine was used before the Christian era in Asia, mainly in India. The introduction of cannabis in the Western medicine occurred in the midst

    of the 19th century, reaching the climax in the last decade of that century, with the availability and usage of cannabis extracts or tinctures. In the first decades

    of the 20th century, the Western medical use of cannabis significantly decreased largely due to difficulties to obtain consistent results from batches of plant

    material of different potencies. The identification of the chemical structure of cannabis components and the possibility of obtaining its pure constituents were

    related to a significant increase in scientific interest in such plant, since 1965. This interest was renewed in the 1990's with the description of cannabinoid

    receptors and the identification of an endogenous cannabinoid system in the brain. A new and more consistent cycle of the use of cannabis derivatives as

    medication begins, since treatment effectiveness and safety started to be scientifically proven."

    "History of Cannabis as a Medicine: A Review," Revista Brasileira de Psiquiatria, June 2006

    "Cannabidiol: From an Inactive Cannabinoid to a Drug With Wide Spectrum of Action," Revista Brasileira de Psiquiatria, Apr. 17, 2008

    "History of Cannabis as a Medicine: A Review," Revista Brasileira de Psiquiatria, 2006

    Cowritten with J.A.S. Crippa, J.E.C. Hallak, F.A. Moreira, and F.S. Guimarães, "Cannabidiol, a Cannabis Sativa Constituent, as an Antipsychotic Drug," Brazilian

    Co-author, "Brain Effects of Cannabis–Neuroimaging Findings," [Article in Portuguese] Revista Brasileira de Psiquiatria, 2005

    Co-author, "Cannabidiol Increases Fos Expression in the Nucleus Accumbens but not in the Dorsal Striatum," Life Sciences, 2004

    Co-author, "Effects of Cannabidiol (CBD) on Regional Cerebral Blood Flow," Neuropsychopharmacology, 2004

  • CBD helps my son with his PTSD, and check out testimonials on this facebook page from a mom I personally know that used CBD for 1 week on her son who had been having over 100 seizures per day and is now seizure free. Plus the picture of this little girl after being on CBD for 1 week is worth a million words!!!!!!

  • Informative video but can't STAND the background music. Geez!

  • This was posted 2011. Does it really make cancer cell commit suicide and fight off infection. You'd think in 2015 that would be in the news. I never heard of CBD before. Unless CBD is what they are giving people with seiners. I have seen that on the news.

  • Over doze on thc ??? You would need to ingest 15000 lbs ?? That's impossible

  • Barbra Streisand? is that you? Sing for us, babe!

  • Please join our facebook page called "LEARN YOUR CBD's".

  • where can i get cbd weed to ship in with little thc so i get the high just enough to enjoy it and not having panick attacks ?

  • God Bless????

  • I'd never heard of CBD until literally minutes ago. Fascinating!….

  • Where can I get this stuff for my seizures? 

  • I just started to have bad anxiety problems especially when i stay up all night. Its like if i am sleepy and i override that i get bad anxiety to the point i can't go to sleep anymore. Sometimes it gets so bad i receive heart palpitations, I think i am going to pick me up some hemp. It all started about 3 months ago, i attempted to go to sleep on a full stomach, and i had a bad anxiety trip, now every time i go bed that's all i can think about and it sets my anxiety off.

  • Thanks for the video! We will be sharing this without a doubt. Education is crutial

  • I just shaved my balls !!!